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We all love to look at tops, maybe this will be useful to you :) Oxymetholone (Anadrol, Anapolon) Oxymetholone is a potent oral anabolic steroid derived from dihydro-testosterone, and its effect on body composition is comparable to that of testosterone. However, while the effect of testosterone is often stated as having an immediate effect upon muscle strength and size, Oxymetholone may also have anabolic effects upon fat loss through reducing cellular synthesis of fat and inhibiting triglyceride synthesis via the reduction and reduction of prostaglandin E2 and Trenbolone-binding proteins [11,12]. Because testosterone has been shown to decrease insulin sensitivity and cause glucose intolerance in humans when tested with the Human Growth Hormone assay, it has been suggested that oxymetholone may also act through its actions on insulin resistance and appetite regulation. Oxymetholone also contains a naturally occurring steroidal molecule with similar actions to that of testosterone, which is termed anandamide . Oxymetholone is primarily metabolized by hepatic catabolism as the synthetic product aldosterone. Aldosterone and allocanol (N-propanolone sulfate) are widely used in weight loss protocols as an oral anabolic steroid. They are also commonly shown to have anabolic actions by decreasing insulin concentrations, increasing substrate metabolism, and reducing serum testosterone levels. Studies have shown that anandamide improves energy intake, increases lean mass for postprandial increases in lean tissue mass, and accelerates energy expenditure. Thus, in addition to its effects on body structure, it appears that anandamide also seems to impact energy and fat metabolism in a manner similar to that of anabolic steroids. It should be noted that although anandamide has been shown to decrease insulin sensitivity, there are no data that anandamide may have an effect on fat storage. In particular, the mechanisms of anandamide's effects are not known and could potentially exist solely through its actions on adipocyte metabolism. Other Anabolic Steroids There are at least 27 clinically-administered anabolic steroids for which there is no evidence that anabolic effects are mediated by the effects of their metabolites. There have been two different studies that attempted to separate out the effects of their individual metabolites from those of anabolic steroids. The first study, conducted by T.O.F. and performed on male mice, aimed to determine which of the various agents studied would be most effective at improving insulin sensitivity in vivo by interfering with hepatic oxidation of the anhydrous form of the hormone as well as increasing fat storage . Unfortunately, the rodents used in the study had lost approximately two percentage points of fat mass in the short periods Similar articles: